Take-home: The use of epi-on photorefractive intrastromal cross linking reduced myopia by about 0.25 D in a small study; In a high-oxygen group, the effect averaged 1.25 D.
Photorefractive intrastromal crosslinking—or PiXL for short—may be a potential new treatment for low-grade myopia, according to Anders Behndig, MD, Department of Clinical Sciences/Ophthalmology, Umea University Hospital, Umeå, Sweden.
Dr. Behndig presented information about his ongoing study, which included healthy volunteers with myopia in the range of -0.5 and -2.6 D (mean, -1.5 D).
All volunteers had epithelium-on (epi-on) PiXL treatment. This treatment included the use of topical anesthesia, isotonic riboflavin that was applied every 90 seconds for 10 minutes, and pulsed crosslinking. A circular central 4-mm cornea zone was irradiated with 30 mW/cm2 for 16:40 minutes.