Take-home message: Autologous serum drops, amniotic membrane, and scleral lenses offer advanced options for management of persistent epithelial defects refractory to standard treatment modalities.
Baltimore—Advanced medical and surgical approaches are helping to address the challenge of treating persistent epithelial defects (PED).
In addition, several novel investigational strategies are also showing promise for the management of this uncommon, but potentially sight-threatening condition, said Bennie H. Jeng, MD.
“Conventional medical management of PED can be arduous for the ophthalmologist and a burden on the patient,” said Dr. Jeng, professor and chairman, Department of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore.
“Surgical options exist when standard medical therapies fail, but several advanced treatment modalities have been proven to be very useful,” he said. “Should all else fail, experimental approaches are also under investigation and showing promise for helping our most challenging cases.”