Similar safety outcomes
In actual use, the two lenses show similar safety outcomes. In a retrospective comparison of the Comfort lens (1,281 eyes) and the Symfony lens (53 eyes) outcomes with presurgical assessment and follow up out to 90 days after implantation, there were no eyes with a loss of two or more lines and no significant difference between mean corrected visual acuities.
The two lenses are also similar in terms of predictability, with no significant difference between the mean spherical equivalent.
Binocular uncorrected defocus curves after surgery are also similar. Both lenses have good multifocal capability. The Symfony lens shows slightly better visual acuity at intermediate distances and the Comfort lens is slightly better at far. Where the two lenses differ is photopsic phenomena, especially halo and glare.
Photopsia is a function of the different optical parameters in the two lenses, Dr. Breyer explained. Due to its higher intermediate addition, the Symfony lens allows users to read smaller print without glasses compared to the Comfort lens, but from experience, the Comfort lens produces less halos and glare.
“Patients have to make a choice of what is more important–being able to read small print without glasses or being without halos and glare,” Dr. Breyer said. “If you want to be on the safe side, the refractive IOL is less trouble for patients because they do have less halos and glare.
“But not every patient is afraid of halos and glare because they do not drive so much in the nighttime,” he added. “How happy the patient is with their lens depends very much on them choosing the right lens for their life and lifestyle.”