Ocular symptoms present
Dr. Crozier, who had been working in an Ebola treatment unit in Sierra Leone, was treated for 40 days then discharged when blood and urine tests for the virus were negative. But 14 weeks after his initial diagnosis, he developed ocular symptoms.
As his condition worsened, Dr. Yeh and Jessica G. Shantha, MD from the Emory Eye Center, along with infectious disease physicians from the Emory University Hospital Serious Communicable Diseases Unit, intervened with procedures including a paracentesis of the anterior chamber.
“That led to the identification of live Ebola virus in the eye both by culture and also by molecular testing,” Dr. Yeh said.
Dr. Crozier was treated with a combination of oral, topical, and local corticosteroids and an oral antiviral medication. His symptoms improved over several months, and he subsequently has returned to Liberia and Sierra Leone to continue his volunteer work with Ebola survivors.