Mouse model studies explore role of matrix metalloproteinase 9 (MMP9) in glaucoma-related axon loss. Initial findings revealed a significant difference in relative axon loss between the MMP9 knockout mice and wild-type control mice.
New research in a large family affected with autosomal dominant juvenile-and adult-onset primary open-angle glaucoma has shown that age of onset can predict severity of disease. Researchers also have demonstrated that at least one modifier gene or locus alters the severity of glaucoma caused by a particular myocilin mutation.
Upgrades to specific confocal laser scanning systems (Heidelberg Retina Tomograph [HRT] and Heidelberg Retina Angiograph 2 [HRA 2], Heidelberg Engineering) should increase the utility of the devices, according to two physicians who have evaluated the new technology.
Las Vegas—Studies of a 790-nm titanium-sapphire laser (SOLX 790, OccuLogix) used to perform trabeculoplasty in human donor eyes and in patients suggest that the laser may be an important tool for treatment of open-angle glaucoma due to benefits such as an IOP-lowering effect, low complication profile, and ability to repeat treatment periodically, according to Gabriel Simon, MD, PhD. He presented a poster on the findings of his research here at the annual meeting of the American Academy of Ophthalmology in Las Vegas.
Las Vegas—Ocular allergies affect up to 40% of the pediatric population, and this high prevalence has ramifications beyond providing symptom relief, said Terry Kim, MD, during a continuing medical education symposium here at the annual meeting of the American Academy of Ophthalmology.
Las Vegas—Identification and pretreatment of allergy patients can improve refractive surgical outcomes, said Deepinder K. Dhaliwal, MD, at a continuing medical education symposium at the American Academy of Ophthalmology annual meeting. About 20% to 30% of refractive surgery patients have associated allergies, she added.
Las Vegas—Steady-state visual evoked potential (SSVEP) is a promising research tool for vision assessment in the preverbal patient and one that is being used increasingly in the clinic, said William V. Good, MD, who discussed his research here during the annual meeting of the American Academy of Ophthalmology.
The shunt takes advantage of the naturally occurring pressure differential between the anterior chamber and the suprachoroidal space.
Las Vegas—Studies have found conflicting evidence that sleep apnea is a risk factor for glaucoma, with variable control groups and variability in defining sleep apnea and glaucoma contributing to the disagreement. Parag A. Gokhale, MD, speaking here at the annual meeting of the American Academy of Ophthalmology, said he sides with those who believe that a positive association exists between the two conditions.
Las Vegas—Laboratory experiments involving an overpressurization technique have demonstrated that acoustic transient cavitation is necessary to produce efficient phacoemulsification, according to Mark E. Schafer, PhD, speaking here at the annual meeting of the American Academy of Ophthalmology (AAO).